adherens junctions造句

• PVRL1 is adhesion molecule found in a wide range of tissues where is localizes in various junctions such as the adherens junction of epithelial tissue or the chemical synapse of neurons.
• The nectin-afadin system organizes adherens junctions cooperatively with the cadherin ( see MIM 192090 )-catenin ( see MIM 116805 ) system in epithelial cells . [ supplied by OMIM]
• Molecular, biological, and comprehensive studies have shown that intercalated discs consist for the most part of mixed type adherens junctions, termed composite junctions or areae compositae ( singular area composita ).
• This internalization of one cell by another is dependent on adherens junctions, and is driven by a Rho-dependent process, involving actin polymerization and myosin II activity in the internalized cell.
• Translocation of ?-catenin from adherens junctions to the hypoxia, can contribute to CSC survival and metastatic potential through stabilization of hypoxia inducible factors through interactions with ROS ( reactive oxygen species ).
• Transgenic mice homozygous for a null mutation of the " JUP " gene die around embryonic day 12 from substantial defects in adherens junctions and a lack of functional desmosomes in the heart.
• PTPkappa interacts by co-immunoprecipitation with E-cadherin, ?-catenin and ?-catenin in pancreatic acinar cells prior to the dissolution of adherens junctions in a rat model of pancreatitis.
• Similar to adherens junctions, the intracellular domains of tight junctions interact with different scaffold proteins, adapter protein s and signaling complexes to regulate cytoskeletal linking, cell polarity, cell signaling and vesical trafficking.
• In cardiomyocytes, ?E-catenin is present in cell to cell regions known as adherens junctions which lie within intercalated discs; these junctions anchor the actin cytoskeleton to the sarcolemma and provide strong cell adhesion.
• These complexes, which help regulate cell growth in addition to creating and maintaining epithelial layers, are known as adherens junctions and they typically include at least cadherin, ?-catenin, and ?-catenin.