ugt1a1造句
例句与造句
- In 2005, the FDA made changes to the labeling of irinotecan to add pharmacogenomics recommendations, such that irinotecan recipients with a homozygous ( both of the two gene copies ) polymorphism in UGT1A1 gene, to be specific, the * 28 variant, should be considered for reduced drug doses.
- However, several allelic dinucleotide repeat TA to the promoter region, resulting in A ( TA 7 ) TAA, which is called " UGT1A1 * 28 "; this common variant accounts for about 40 % of alleles in some populations, but is seen less often, around 3 % of alleles, in Southeast and East Asian people and Pacific Islanders.
- More than 100 variants of the " UGT1A1 " gene are known, designated as " UGT1A1 * n " ( where n is the general chronological order of discovery ), either of the gene itself or of its promoter region . " UGT1A1 " is associated with a TATA box promoter region; this region most commonly contains the genetic sequence A ( TA 6 ) TAA; this variant accounts for about 50 % of alleles in many populations.
- More than 100 variants of the " UGT1A1 " gene are known, designated as " UGT1A1 * n " ( where n is the general chronological order of discovery ), either of the gene itself or of its promoter region . " UGT1A1 " is associated with a TATA box promoter region; this region most commonly contains the genetic sequence A ( TA 6 ) TAA; this variant accounts for about 50 % of alleles in many populations.
- More than 100 variants of the " UGT1A1 " gene are known, designated as " UGT1A1 * n " ( where n is the general chronological order of discovery ), either of the gene itself or of its promoter region . " UGT1A1 " is associated with a TATA box promoter region; this region most commonly contains the genetic sequence A ( TA 6 ) TAA; this variant accounts for about 50 % of alleles in many populations.
- It's difficult to find ugt1a1 in a sentence. 用ugt1a1造句挺难的
- However, Gilbert's syndrome can arise without TATA box promoter polymorphic mutations; in some populations, particularly healthy Southeast and East Asians, Gilbert's syndrome is more often a consequence of heterozygote missense mutations ( such as Gly71Arg also known as " UGT1A1 * 6 ", Tyr486Asp also known as " UGT1A1 * 7 ", Pro364Leu also known as " UGT1A1 * 73 " ) in the actual gene coding region, which may be associated with significantly higher bilirubin levels.
- However, Gilbert's syndrome can arise without TATA box promoter polymorphic mutations; in some populations, particularly healthy Southeast and East Asians, Gilbert's syndrome is more often a consequence of heterozygote missense mutations ( such as Gly71Arg also known as " UGT1A1 * 6 ", Tyr486Asp also known as " UGT1A1 * 7 ", Pro364Leu also known as " UGT1A1 * 73 " ) in the actual gene coding region, which may be associated with significantly higher bilirubin levels.
- However, Gilbert's syndrome can arise without TATA box promoter polymorphic mutations; in some populations, particularly healthy Southeast and East Asians, Gilbert's syndrome is more often a consequence of heterozygote missense mutations ( such as Gly71Arg also known as " UGT1A1 * 6 ", Tyr486Asp also known as " UGT1A1 * 7 ", Pro364Leu also known as " UGT1A1 * 73 " ) in the actual gene coding region, which may be associated with significantly higher bilirubin levels.
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