ldlr中文什么意思
abbr. low density lipoprotein receptor 低密度脂蛋白受体
例句与用法
- apolipoprotein e, a 34kda protein composed of 299 amino acids, is a multifunctional molecular, which is an important functional component of chylomicrons and very low density lipoprotein, intermediate density lipoprotein and high density lipoproteins . as a ligand for the low density lipoprotein receptor ( ldlr ), it plays an important role in the metabolism of plasma lipoproteins
载脂蛋白e(apoe)是34kda大小的多功能分子,由299个氨基酸组成,是cm、vldl、idl和部分hdl的组分,通过ldl受体途径调控脂蛋白代谢,在脂类代谢中发挥重要作用。 - apoe2 binds poorly to the ldlr, and homozygous inheritance of the apoe2 allele is strongly associated with type iii dyslipoproteinemia . apoe2 and apoe4 are associated with hypercholesterolemia and atherosclerosis ( as ) . the apoe4 is also associated with higher incidence and earlier age of onset of late onset familial alzheimer's disease ( ad ), whereas apoe2 may have the opposite effect
apoe_2与ldlr结合能力很差,与型高脂血症关联。apoe_2和apoe_4与高胆固醇血症、动脉粥样硬化(as)等疾病有关,apoe_4还是老年痴呆(ad)的高发风险因子,而apoe_2则对预防老年痴呆病的发生具有积极作用。