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- 1 effect of cck - 8 on changes in lung and spleen of es rats 1 . 1 cck - 8 attenuates morphologic and functional changes in lung and spleen of es rats to observe the effect of cck - 8 on decrease of mean arterial pressure ( map ) induced by lps and ultrastructure changes in lung and spleen of es rats , animals were randomly assigned to four groups injected different agents via tail vein
)复制的大鼠es模型工ps注入前10min尾静脉注入cck七k011g kgtv x单独注入cck七k0pg kgtv )或生理盐水(对照)的四组大鼠血压的改变,应用光镜观察各组注药后2h 、 6h 、 12h肺脏和脾脏结构改变。