1. Bronopol was invented by The Boots Company PLC in the early 1960s and first applications were as a preservative for pharmaceuticals.
  2. The use of bronopol in personal care products ( cosmetics, toiletries ) has declined since the late 1980s due to the potential formation of nitrosamines.
  3. Manufacturers of personal care products are therefore instructed by regulatory authorities to'avoid the formation of nitrosamines'which might mean removing amines or amides from the formulation, removing Bronopol from a formulation, or using nitrosamine inhibitors.
  4. Stardrops cleaner : Sodium dodecylbenzene sulphonate, Alkyl ether sulphate, Alcohols C9-11, ethoxylated Bitrex ( Denatonium benzoate ) solution, Bronopol ( 2-bromo-2-nitropropane-1, 3-diol ).
  5. Owing to its low mammalian toxicity ( at in-use levels ) and high activity against bacteria ( especially the troublesome Gram-negative species ), bronopol became popular as a preservative in many consumer products such as shampoos and cosmetics.
  6. It's difficult to find bronopol in a sentence. 用bronopol造句挺难的
  7. While Bronopol is not in itself a nitrosating agent, under conditions where it decomposes " ( alkaline solution and / or elevated temperatures ) " it can liberate nitrite and low levels of formaldehyde and these decomposition products can react with any contaminant secondary amines or amides in a personal care formulation to produce significant levels of nitrosamines ( due to the toxicity of these substances, the term'significant'means levels as low as 10s of parts per billion ).


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