presenilins造句

例句与造句

1. The presenilins are components of proteolytic complex involved in APP processing and degradation.
2. Presenilins are also implicated in the processing of notch, an important developmental protein.
3. Both genes show conservation between species, with little difference between rat and human presenilins.
4. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins.
5. "The abnormal cleavage of presenilins, we believe, may precede all the Alzheimer's pathology.
6. It's difficult to find presenilins in a sentence. 用presenilins造句挺难的
7. Bouton also published on the effects of lead on gene expression and the involvement of presenilins in Alzheimer's Disease.
8. "' Presenilins "'are a family of related multi-pass transmembrane proteins which constitute the catalytic subunits of the gamma-secretase intramembrane protease complex.
9. The nematode worm " C . elegans " has two genes that resemble the presenilins and appear to be functionally similar, sel-12 and hop-1.
10. In 1995, Dr . Peter St . George-Hyslop at the Tanz Centre would go on to discover two genes, called presenilins, associated with the early onset Alzheimer's disease.
11. As mentioned before, STIM2 has been shown to interact with STIM1, The expression of STIM2 has been shown to be influenced or regulated by presenilins in mouse embryonic fibroblasts and human B lymphocytes.
12. Variation in presenilins-associated rhomboid-like protein ( PSARL ) sequence and / or expression may be an important new risk factor for type 2 diabetes and other components of the metabolic syndrome.
13. Presenilins undergo cleavage in an alpha helical region of one of the cytoplasmic loops to produce a large N-terminal and a smaller C-terminal fragment that together form part of the functional protein.
14. The genetic inactivation of presenilins in hippocampal synapses has shown this selectively affects the long-term potentiation caused by theta with the inactivation in presynapse but not the postsynapse impairing short-term plasticity and synaptic facilitation.
15. Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP . Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma secretase activity or themselves are protease enzymes.
16. Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP . Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma secretase activity or themselves are protease enzymes.
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