Follistatin , a kind of secreted protein , is known to antagonise the function of several members of the tgf - beta ( transforming growth factor - beta ) superfamily including myostatin , the most powerful inhibitor of muscle growth characterised to date 卵泡抑素( follistatin )是一种分泌蛋白，它可以拮抗tgf - beta ( transforminggrowthfactor ，转化生长因子)超家族中几种成员的功能，包括myostatin 。
In the immunohistochemical localization study , d - cells lie in the whole digestive tract , the most d - cell presents in stomach ; g - cell is the most in the pyloric gland of stomach ; a - cell is found only in the stomach and small intestine accidentally 免疫组织化学方法发现，生长抑素细胞在整个消化道均有分布，其中在胃底腺和幽门腺最多，小肠和食管中偶见；胃泌素细胞在幽门腺最多，其次是胃底腺和大肠。
This article begins with a brief overview of the discovery of glucagon and the contributions that somatostatin and a sensitive and selective assay for pancreatic ( vs . gut ) glucagon made to understanding the physiological and pathophysiological roles of glucagon 文章的开始简单回顾了胰高糖素的发现过程以及生长抑素和一种能敏感特异的检验胰腺中（与肠道相比）的胰高糖素的方法在帮助人们理解胰高糖素的生理和病理生理作用过程中所发挥的作用。
This article begins with a brief overview of the discovery of glucagon and the contributions that somatostatin and a sensitive and selective assay for pancreatic ( vs . gut ) glucagon made to understanding the physiological and pathophysiological roles of glucagon 文章的开始部分简单回顾了胰高糖素的发现过程，以及其对生长抑素的作用和一项具有高敏感性和特异性的检验胰腺中的胰高糖素的方法（与肠道内的检测法相比） ，来帮助人们理解胰高糖素的生理和病理生理作用。
The bmn cells and fifth instars were infected by the recombinant virus bacpak - angiostatin . the bioactivity of the protein product was determined by human umbilical vein endothelial cells ( ecv304 ) growth assay in vitro and inhibition of vascular growth assay in cam in vivo . angiostatin showed significantly inhibitory effect on endothelial cells 重组病毒以moi = 10感染家蚕细胞( 2 10 ~ 6个细胞/ 5ml )和家蚕5龄幼虫，表达产物用体外培养的人脐静脉血管内皮细胞( ecv304 )及体内鸡胚尿囊膜( cam )新生血管实验检测其抑制活性： (一)血管抑素可明显抑制体外培养的内皮细胞增殖。
Cam assay also showed synergy between angiostatin and endostatin could inhibit the angiogenesis and its effect was stronger than either of angiostain or endostatin . in conclusion , using beys to express angiostatin , we could obtain lots of active angiostatin protein , could also cut down production cost grately and lay a foundation for clinical application 综上所述，运用家蚕杆状病毒表达系统进行表达，可获得大量有生物活性的血管抑素，以满足用临床上大剂量应用，且大幅度降低成本，为今后在临床上的广泛应用打下基础。
The objective of this study is to evaluate the effects of active immunization against ss on nutrient digestion and metabolism , growth and carcass composition of the growing hu - sheep ; 2 , on the ss secretion in fundus , antrum and pancreas and the ablity of the antibodies to integrate free ss ; 3 , on passage rates of digesta ; 4 , on activities of digestive enzymes in pancreas and digesta ; 4 , on gene expression of gh in pituitary 本项研究内容集中于后者，主要的试验目的是： 1生长抑素主动免疫对ss进行免疫中和对生长期湖羊生长，营养物的消化，代谢，胴体组成影响； 2对胃窦膜，基底膜和胰腺ss分泌以及ss抗体结合ss的能力影响； 3
In addition , the stomach contained glu - ir cellsn gas - ir cells and vip - ir cells , and the duodenum contained glu - ir cells and gas - ir cells . different endocrine cells varied from one to another in the distribution pattern , the stage of appearance and the number . no glu - ir cell , gas - ir cell or vip - ir cell was found in the oesophagus and no vip - ir cell in the duodenum 另外，胚胎期扬子鳄消化道内分泌细胞的种类和分布与成体有差异，胚胎期消化道检出胰高血糖素、胰多肽和p物质免疫阳性细胞，而成体未检出；胚胎期消化道中胃泌素、血管活性肠肽，生长抑素免疫阳性细胞分布与成体消化道不同。
At present , the main methods used in the study on chinese traditional medicine in gastrointestinal dynamics animal experiment are gastric emptying and small intestine motional rate mensuration , parent electric bridge strain gauge mensuration , gut hormone determination ( gas , mot , ss et ) , immunohistochemical method , excised gastrointestinal smooth muscle dynamoscopy , intragastric and intestine pressure tracing 摘要中药在胃肠动力动物基础实验研究，目前主要采用胃排空小肠推进率测定法、胃肠道腔外电桥式应力传感器记录法、胃肠激素测定（胃泌素、胃动素、生长抑素等） 、免疫组织化学方法、离体体胃肠平滑肌肌条动力测定、胃肠内压描记法。
The endocrine cells in the digestive and glands of alligator sinensis embryos aged from 8th to 55th day were localized and compared by using immunohistochemical method with thirteen kinds of antiseras of hormone . during the development of pancreas in alligator sinensis embryos , somatostatin ( ss ) immunoreactive ( ir ) cells , 5 - hydroxytryptamine ( 5 - ht ) - ir cells , glucagon ( glu ) - ir cells , epidermal growth factor ( egf ) - ir cells appeared on 18th day . no p53 protein - ir cell , gastrin - ir cell , testosterone - ir cell , chromogranin a - ir cell , vasoactive intestinal polypeptide - ir cell , epithelial membrane antigen - ir cell or insulin - ir cell was found in the pancreas of alligator sinensis embryos 本实验采用免疫组织化学技术，应用13种不同的抗血清，对孵育时间8 ? 55天扬子鳄胚胎消化道及消化腺内分泌细胞的种类进行鉴别、定位和比较，结果如下：扬子鳄胚胎胰腺中，生长抑素、 5 ?羟色胺、胰高血糖素、表皮生长因子、胰多肽免疫反应阳性细胞出现于第8天； p物质免疫阳性细胞出现于第18天； p53 、胃泌素、睾酮、嗜铬素a 、血管活性肠肽、上皮膜肮原、胰岛素免疫阳性细胞在各期扬子鳄胚胎胰腺中均未发现。
