Prolonged inflammation leads to reduced activity of fingers , and can result in muscle weakness and wasting . if there is also improper posture and activity , there may be permanent joint deformity 长期关节发炎会令手指活动减少，引致肌肉萎缩无力，倘若加上手指长期处于不正确的活动及姿势，便可能导致永久性关节变形。
Prolonged inflammation leads to reduced activity of fingers , and can result in muscle weakness and wasting . if there is also improper posture and activity , there may be permanent joint deformity 长期关节发炎会令手指活动减少，引致肌肉萎缩、无力，倘若加上手指长期处于不正确的活动及姿势，便可能导致永久性关节变形。
Unilateral more incidence of lower limb , foot and leg initial cold , afraid of the cold , numb , intermittent claudication , pain , muscle atrophy began to emerge , gan mao peeling and serious ulcers can occur or gangrene 以单侧下肢发病较多，起始足部和小腿发凉，怕冷，麻木，间歇跛行，疼痛，逐渐出现肌肉萎缩，汗毛脱落，严重者可发生溃疡或坏疽。
Researchers at johns hopkins hae shown that a drug commonly used to lower blood pressure reerses muscle wasting in genetically engineered mice with marfan syndrome and also preents muscle degeneration in mice with duchenne muscular dystrophy 约翰*霍普金斯的研究人员表示一种通常被用于降低血压的药物逆转了患有马凡综合征的基因工程小鼠的肌肉萎缩。
The movements of the princes small foot in its tatar , silver - embroidered boot , the firm pressure of his sinewy , lean hand , showed the strength of vigorous old age still strong - willed and wiry 从他用以操作的那只穿着绣有银线的鞑靼式的皮靴的不大的脚来看，从青筋赤露肌肉萎缩的手上磨出的硬皮来看，公爵还具有精神充沛的老人的百折不回的毅力和极大的耐力。
Over the years , the scheme has provided travel opportunities for the underprivileged , including children with incurable diseases taking flight to disneyland , neuromuscular disease sufferers , and others in need to travel abroad for life - saving surgery “国泰慈善旅游基金”成立以来帮助了很多有需要的人，其中包括赞助病童前往迪士尼乐园患上肌肉萎缩症的病人远赴海外接受手术等。
To the memory of joel " espy " klecker , a debian developer , unbeknownst to most of the debian project , was bedridden and fighting a disease known as duchenne muscular dystrophy during most of his involvement with debian 给刚刚逝去的debian热心开发者joel " espy " klecker 。 joel一直被困在病床上。他患的是“杜兴氏肌肉萎缩症” duchenne muscular dystrophy一种基因缺陷造成的不治之症。
Set up on the cathay pacific s 50th anniversary year , the program was aimed to raise funds to purchase specially adapted wheelchairs for children with neuromuscular diseases . to date , the wheelchair bank maintains about 152 wheelchair for use by more than 160 children 为庆祝金禧纪念，国泰航空于1996年成立国泰爱心儿童轮椅库，为轮椅库筹募款项，用以为本地不幸患上肌肉萎缩症的病童从海外购买备有身体承托系统的坐姿矫正轮椅，以改善他们的生活。
The side outside my mom ham appears cave , transverse and straighter , the doctor says is to become suddenly thin be caused by , but such circumstance also has appeared when my mom colleague suffers from sweeny , we are so afraider , the meeting after becoming whether suddenly thin has such case 我妈妈大腿外侧出现凹陷，横向且较直，有医生说是忽然变瘦所致，但我妈同事患肌肉萎缩时也出现过这样的情况，所以我们都比较担心，是否忽然变瘦后会有这样的情况？
Elevation of intracellular calcium ions may be partly induced by increased influx through sarcolemma l type - calcium channels . intracellular calcium elevation , on one hand , would activate calpain , a calcium - dependent cysteine protease that degrade the myofibrillar proteins and cause muscle atrophy ; on the other hand , result in activation of calcineurin which enhance the activity of mhc i promoter and inhibit a shift of mhc isoforms from slow to fast in soleus 这样，可能使得萎缩比目鱼肌细胞内钙离子水平升高，细胞内钙离子静息浓度的增加一方面激活calpain ，增加收缩蛋白的降解，使肌肉萎缩；草四军医大月卜祠成士学位论文另一方面通过激活钙调神经磷酸酶，增加快型mhc基因的表达，使骨骼肌肌球蛋白重链( mhc )发生由慢型向快型的转化。
