Methods the heat stroke model was established under circum stances of dry buld temperature ( 34 . 5 0 . 5 ) and ( 60 5 ) % relative humidity . 40 mice were randomly divided into five groups including reduping group , xihuangqijiao group , dexamethasone group , heat strike group and normal group and the increased rate of temperature , subsistence time and the number of diarrhea of experimental animals were observed 方法在干球温度( 34 . 5 0 . 5 ) ，相对湿度( 60 5 ) %的条件下建立小鼠中暑模型，将40只小鼠随机分为热毒平组、西黄芪胶组、高温中暑组、地塞米松组和正常对照组，观察动物的肛温上升速率、存活日寸间和致泻作用。
L lp - hsdl ma of i . 5kb was detected in the rna extracted from cult ' ured chorionic trophoblast using northem blot hybridhation method . the expression of ll6 - hsdl wa was induced by treating the chorionic cells with dexamethasone ( l0 - ' , l0 ' m ) for 24h , and the induction was blocked by co - treatinent of the cells with ru486 . these results suggest a gr - mediated effect of glucocorticoid on the rnrna expression and reductase activity of l l 9 - hsd1 人h合成的肌?一加x门’ m ）对培养的绒毛膜滋养层细胞的11p hsdi还原酶活性具有诱导作用，此诱导作用可以被gr阻断剂ru486门0川）所阻断； northern印迹杂交方法进一步证实， dex亦可诱导绒毛膜滋养层细胞11p叫inrna的表达，此诱导作用也可以被ru486门0叫川）所阻断
Upon the differentiation induction of 3t3 - l1 preadipocytes by hormone cocktail containing 1 - isobutyl - 3 - methylxanthine , dexamethasone and insulin , the preadipocytes undergo ~ 2 rounds of mitotic clonal expansion , which just precedes the adipogenic gene expression program and has been thought to be an essential early step for differentiation initiation 诱导分化的早期细胞会进行约两轮的细胞分裂，被称为克隆扩增。克隆扩增以前一直被认为可能有利于染色体的重构以易化分化所需要的基因表达，因此克隆扩增可能是3t3 l1前脂肪细胞分化所必需的过程。
