Beneath the capsule is the paracortical zone with lymphoid follicles having a pale germinal center in which the immune responses are often generated 被膜下方是有淋巴滤泡的副皮质区,淋巴滤泡有一苍白色的生发中心。
The result of experiment shows that the magnetic treatment can improve efficacy of antibacterial agents and deal with the problem of germinal medicine - resistance 其结果表明,磁场处理能提高抗菌药物的疗效,对解决细菌耐药性问题有一定的参考价值。
Within 2h isolation from the follicle 100 % of oocytes underwent germinal vesicle breakdown and both the nucleolus and the nuclear envelope disappeared . after culturing for 6 h , prometaphase occurred in 90 % oocytes 本研究旨在探索一种崭新的、化学试剂诱导去核卵母细胞为核受体的、无透明带的、手工体细胞核移植方法。
At high magnification , the germinal center in this reactive lymph node follicle has prominent macrophages with irregular cellular debris ( so - called " tingible body macrophages " ) . blood vessels are also more prominent 高倍镜下反应性淋巴结滤泡的生发中心有明显的含不规则细胞碎片的巨噬细胞(称为“易染体巨噬细胞” ) 。血管也是非常明显的。
Adam smith , whose the wealth of nations ( 1776 ) is the germinal book of modern economics , was thrilled by the recognition of an order in the economic system , smith proclaimed the principle of the “ invisible hand " 亚当.斯密斯所写的国富论( 1776 )是现代经济学的开元之作.他认识到了经济体系中所存在的秩序,这一点让他颇感意外.于是,斯密斯提出了"看不见的手"这一规则
The pollen grains with different ecological style of germinal apertures in length , width , length and width of lid , shape of lid and the extent of protuberances etc . , especially with several hollows could be the factors resulting in the different germination of pollen 在花粉群体的观察中发现:花粉萌发率最低的杰兔品种花粉粒中,有明显“干瘪”形状的花粉粒比例高达80 . 00 % 。
Germinal vesicle ( gv ) transfer is a technique developed in recent years , which may be a valuable research procedure to study cell cycle regulation and characterize the cytoplasmic - nuclear interplay during maturation and fertilization of oocytes 生发泡( gv )移植是最近几年才建立起来的一种技术。通过gv移植可以研究细胞周期调控、成熟及受精时细胞核与细胞质之间的相互作用。
Spf chickens with 21 - day - old were infected subcutaneously with oil - emulsion vaccine of ibdv of germinal or cellcular and injected intramuscularly with different dosages bursin which gain through ultrafilter . lt is proved that bursin of chickens and ducks can both shorten the time of antibody induced against ibdv , raise the level of serum antibody . they make chickens obtaining strong immunocompetente in a short time . agp liters of the group of infecting 0 . 4mlcbs + ibdv of germinal and 0 . 8mlcbs + ibdv of cellcular or 0 . 8mldbs + ibdv of germinal and cellcular are higher than immune control group about 2 liters averagely . the chickens were inoculated with ibdv live vaccine mixed with the different dosages of lyophilized bursin by the eye drop method . the results sugest that cbs or dbs of different dosages can both improve the antibody inducation to different age chickens against ibdv . they may also alleviate the immunological injury of activated virus to bursa of fabricius . and promote the repairation of the lesion . it can be found that bs can raise body weight gain and feed coversion ratio 将超滤获得的法氏囊活性肽分别以不同剂量肌肉注射21日龄spf鸡,同时颈部皮下注射ibd胚毒或细胞毒灭活苗,结果表明:鸡、鸭法氏囊活性肽都能够缩短ibd油苗诱导产生抗体的时间,提高抗体水平,使鸡可以在比较短的时间内获得坚强的免疫。 0 . 4mlcbs胚毒组和0 . 8mlcbs细胞毒组或0 . 8mldbs胚毒和细胞毒组的agp抗体滴度平均比免疫对照组高2个滴度。将法氏囊活性肽与ibd活苗联合免疫鸡,结果表明:不同剂量的cbs和dbs都可以对不同日龄鸡ibd抗体的产生有不同程度的促进作用;还可以减少弱毒对鸡法氏囊组织的损伤,加快其修复。
Protein kinase a is camp - dependent kinase , one of the most important signal transduction pathways , plays a pivotal role in growth , differentiation , tumor occur , cell cycle control , etc . pka activators such as camp , 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes , also in xenopus oocytes 蛋白激酶a ( proteinkinasea , pka )是依赖于camp的丝苏氨酸蛋白激酶,是重要的信号传导途径之一,广泛参与许多生命过程,包括生长、分化、肿瘤发生、细胞凋亡、细胞周期调控等。以小鼠卵母细胞为实验对象,给予pka激动剂camp 、 8 - br - camp或磷酸二酯酶抑制剂imbx ( isomethylbutylxanthine )均可抑制小鼠卵母细胞的胚泡破裂及减数分裂成熟。
Rat cumulus - enclosed oocyte ( ceo ) and denuded oocyte ( do ) both spontaneously resume meiotic maturation in vitro , when cultured for 2h , the germinal vesical breakdown percentage of do reaches up to 88 % , and ceos get 53 % . oocytes begin to extrude first polar body 1 ( fb1 ) when cultured for 8h . mouse oocyte spontaneous maturation in vitro can be inhibited by 4mm hypoxanthine ( hx ) or 25um 3 - isobutyl - methylxanthine ( ibmx ) . while , 4mm hx can not inhibit the spontaneous maturation of rat oocyte , and the lowest effective concentration of ibmx to inhibit rat oocyle spontaneous maturation in vitro is 50um . treated with the same concentration of ibmx , gvbd percentage of rat ceo is lower than that of do , the results indicat that cumulus cells delay rat oocyte spontaneous maturation and potentate the inhibition effect of ibmx , but it ' s not the case on mouse Ceo和do培养8h时都开始排出pb1 ;在卵母细胞成熟抑制模型中, 4mm次黄嘌呤( hx )和25 m的异丁基甲基黄嘌呤( ibmx )是小鼠卵母细胞成熟的有效抑制剂,但4mm的hx抑制大鼠卵母细胞成熟效果不理想,用hx - m199和hx - mem培养24h , gvbd率分别为61 , 81 ,而ibmx有效抑制大鼠卵母细胞自发成熟的最小浓度为50 m , ibmx可以降低大鼠ceo和do的gvbd率,但ceo中的卵母细胞gvbd率要显著低于do的gvbd率, 100 m的jbmx处理24h后,大鼠ceo和do的gvbd率分别为24 , 84 ,提示卵丘细胞的存在可以延迟大鼠卵母细胞的自发成熟,有助于抑制卵母细胞成熟,但在小鼠上ceo和do的自发成熟差异不明显。