Study on monascus pigment production by fed - batch fermentation of glucose solution with immobilized monascus purpureus 固定化红曲葡萄糖母液流加发酵红曲色素的研究
The production experiment of red koji was conducted with millet as raw material and monascus purpureus being inoculated 摘要红曲是一种天然红色素，传统生产工艺以籼米为原料。
Accordingly , the discovery of citrinin in monascus brought tremendous dispute about the safety of red starter products 红曲霉中桔霉素的发现使得我国的红曲产品的安全性引起争议。
Also , the anti - tumor function of lovastatin hi vivo was assessed utilizing monascus mber containing lovastatin 研究结果显示， lovastatin能有效抑制人肺癌d6细胞株的增殖，并诱导其凋亡。
Conclusion : this study may serve as deposing the evidences to classify monascus fungi and to identify hongqu 结论：红? ?的扫描电镜观察为该属真菌的分类提供依据并为中药红?的生药鉴定提供佐证。
However , citrinin , produced in the growth process of monascus , is a mycotoxin and will induce teratogenicity , carcinogenicity and mutagencity 桔霉素是一种真菌毒素，作用的靶器官是肾脏，可以致畸、诱发肿瘤、突变等。
Monascus , as a physiologically active substance and an old - line fermentable epiphyte in china , has been studied widely for its natural pigments 摘要红曲霉能代谢生成天然红色素和多种生理活性物质而备受国际关注，但同时也发现其生长过程产生桔霉素。
Methods : 7 species of standard strains monascus fungi for preparing hongqu were cultivated on carry sheet glass and observed and compared after pretreatment using the scanning electron microscope 方法：玻片法培养7种常见制备红?用红? ?标准株，预处理后进行扫描电镜的观察和比较。
Through a series of mutagen tests , a mutant strain of monascus spp ( m 12 - 69 ) from ml2 was acquired , which can produce much higher monacolin k than m12 , and almost same citrinin level as m12 以之为出发菌株，通过诱变筛选，获得一株monacolink产率有明显提高而桔霉素产率仅为0 . 13ng g ( elisa )的突变株，编号为m12 - 69 。
Studies on morphological observation and categorization showed that there were several differences between the strain m12 and the mutant strain m12 - 69 , but they both belong to monascus pilosus sato , according to hawksworth and pitt 第四，根据hawkswo曲和pitt关于红曲霉的分类方法，对m12及m12一69的培养物进行了形态观察及分类鉴定。
