The masp ( mannose - binding lectin - associated serine protease ) gene has been cloned by the method of degenerative pcr and the fragment of the pcr product is 630 bps in length 本文还利用pcr方法从青岛文昌鱼基因组dna中克隆masp (甘露聚糖结合凝集素相关丝氨酸蛋白酶)基因片段。
The vfcpkl has an obvious kinase catalytic domain for ca2 + / calmodulin dependent protein kinases and serine / threonine protein kinases , and a calcium - binding domain like calmodulin Vfcpk1具有明显的ca ~ ( 2 + )钙调素依赖蛋白激酶及丝氨酸苏氨酸蛋白激酶的激酶区以及类似于钙调素的钙结合区。
Clr is a complement serine protease , composed of two cub ( clr / cls , an embryonic sea urchin protein uegf , and bone morphogenetic protein i ) domains , one egf domain and one serine protease domain 补体组分c1r含有两个cub结构域,一个egf结构域和一个丝氨酸蛋白酶结构域,是一种丝氨酸蛋白酶原。
Pre - clinical studies showed that sorafenib inhibited tumor cell proliferation and angiogenesis by blocking serine / threonine and receptor tyrosine kinases which were inseparable with tumor growth 临床前研究显示,索拉非尼作用的2种激酶会影响肿瘤细胞增生及血管生成,而此2种行为为肿瘤生长时所不可或缺。
While , in " belami " petals , the metallo - proteinase and the thiol - proteinase activities of the optimum ph 6 and the serine proteinase activities of the optimum ph 10 are also increased markedly 而在‘贝拉米’花瓣中最适ph6条件下金属蛋白酶、琉基蛋白酶和最适ph条件下丝氨酸蛋白酶的活性都显著提高了。
Comparison of the entire derived peptide sequence with other serine protease revealed significant homology , especially with a reported gene from another b . pumilus strain tyo - 67 ( 99 % homology ) 将克隆到的碱性蛋白酶基因(命名为ap )编码的成熟蛋白n一端序列与纯化的脱毛蛋白酶n一端序列进行比较,二者完全相同。
For trypsin - like serine protease domain , the presence of his ( h ) - asp ( d ) - ser ( s ) representing a serine protease catalytic triad were at position of 283 , 339 , 436 , respectively Clsp在正常人外周血单核细胞来源的dc中有较强的表达,在分别经anti一cd40 、 tnf一a 、 lps刺激后的dc中,其表达水平均有所上升。
Cdc25 undergoes serine / thre - onine phosphorylation at mitosis and enhances its phosphatase activity . mpf phosphorylates and actives cdc25 , which in turn dephosphorylates and further activates prempf Pkb分子量60kda ,目前已知分为pkb 、 、三种, pkb akt1广泛存在于机体各组织中,其活性受多种激活剂调节。
The kinase catalytic domain is 264 amino acids in length and contains all of 11 conserved subdomains and 15 invariant amino acid residues essential fo r eukaryotic serine / threonine protein kinases 激酶区长264个氨基酸残基,具有所有11个保守的亚结构域和15个对于真核生物丝氨酸苏氨酸蛋白激酶所必需的保守的氨基酸残基。