Methods cerebral blood flow ( cbf ) and intracranial pressure ( icp ) were measured after electrolytical destruction of the dorsomedial nucleus of the hypothalamus , the midbrain reticular formation , or / and the reticular formation of the medulla oblongata 方法电解毁损家兔下丘脑背内侧核、中脑网状结构和延髓网状结构,观察脑血流量和颅内压的变化。
Results showed that unilateral transection of the middle midbrain above the ventral tegmentum did not block the synchronized bursts on both sides ; however , the synchronized bursts disappeared after unilateral transection through the middle of the medial hypothalamus 结果显示:在腹侧被盖以上横向切断单侧中脑中部,不能阻断双侧催产素神经元的同步化爆发放电;但是单侧下丘脑中间内侧部横切则可阻断这种同步化爆发放电。
In recent years , investigations on the gene expression patterns of multiple tissues in diverse organisms including human , primates and fruit fly has been initiated , and the results indicated that the change of gene expression in human brain is the most significant during human evolution 近年来,对于人和灵长类以及果蝇等其他一些动物多种组织基因表达谱的研究表明,在人的进化过程中脑基因表达的改变最为显著,并且脑中许多基因的表达呈显著上调。
The present study , ( d by using immunohistochemical single , double or triple staining method , showed the expression , relationship and distribution pattern of fos - protein , gfap or th in rat cns , investigated the plastic response and relationship of rat lumbar spinal cord as and neurons to pain induced by the unilateral tibia and fibula fracture ; ( 2 ) by using a double immuno - electron - microscopic method , investigated the ultrastructural characters of junction areas between neurons and as in the dorsal horn of rat lumbar spinal cord following the unilateral tibia and fibula fracture ; ? after intrathecal application of the carbenoxolone , a gap junction blocker , recorded the paw withdrawal thermal latency and compared with control 在脑干gfap - li星形胶质细胞主要分布于mvz内的孤束核( nts ) 、腹外侧延髓( vlm )以第四军医大学博士学位论文及两者之间的中间带( irt )上。三叉神经脊束核尾侧亚核( vc ) 、外侧楔柬核( ecu ) 、蓝斑( lc ) 、臂旁外侧核( lp ) 、中缝大核( rmg ) 、中脑导水管周围灰质腹外侧区( vipag ) 、中缝背核( dr )等部位也出现一定数量的gfap阳性细胞。 f 。
Gonadal steroid hormone , especially estrogen , exerted considerable effects upon the pituitary , hypothalamus , nigrostriatal and mesolimbic dopaminergic ( daergic ) systems , of which , amygdala ( amy ) was one of the most important site affected by estrogen and the main projection site for daergic neurons from midbrain 大量研究证明,性腺类固醇激素可在垂体、下丘脑、黑质?纹状体系统和中脑边缘系统水平影响多巴胺( da )能神经元的功能。其中,杏仁核( amy )是雌激素的重要作用部位之一。
In addition , da release from amy of female , male and ovx rats was monitored after intracerebroventricular ( i . c . v ) injection of estrogen - like medicine , effective contraction of wujibaifengwan and soy isoflavones , to detect the influence of the drugs on the daergic systems of midbrain in the rats 此外,本工作还检测了雌鼠、 ovx鼠和雄鼠侧脑室注射天然的类雌激素药物?乌鸡白凤丸有效成分和大豆异黄酮后,电刺激诱发的amyda释放,从而为研究类雌激素药物对大鼠中脑da能神经系统的影响及指导临床用药提供实验基础和理论依据。
The elf - emfs had no impact on neurite outgrowth . it was concluded that elf - emf , with the advantage of economy , convenience , as well as easy control , might be an effective method ex vivo to manipulate neural progenitors differentiation in stem - cell therapy . the possible mechanism of the elf - emfs effects on neurogenesis of mesencephalic progenitors was further explored Emfs的此效应具有频率特异性,场强也是影响因素; 10 20 40hz ( 8mt ) emfs还可增加衍生于中脑神经前体细胞的th阳性细胞数;但各频率emf对神经突的延伸均无作用。
Amy appeared obvious pathologic changes during the process of parkinson ' s disease ( pd ) caused by dysfunction of daergic neurons , which resulted in special syndromes occurring in partial patients of pd . our previous experiments showed that exogenous estrogen could promote dopamine ( da ) release from amy of ovariectomized ( ovx ) rats Amy也是中脑da能神经元的主要投射部位,在da能神经元功能障碍性疾病帕金森病( pd )的发病过程中, amy发生了显著的病理学变化,导致临床上部分pd病人出现与amy有关的特异性临床症状。
By the analysis of cell cycle disturbution and the examination of mashl , neurod and notchl mrna expression in proliferating or differentiating neural progenitors , the findings implied an important role of neurod in controlling the neuronal fate commitment in mesencephalic neural progenitors from newborn rats 增殖及分化期的新生大鼠中脑神经前体细胞neurod 、中义摘要mashl和notchl基因表达的测定结果表明, neurod基因在新生大鼠中脑神经前体细胞神经元向分化中发挥关键作用。