Resent studies demonstrate that , such as gabaar1 subunit of gaba receptor , ka2 and glur6 subunit of ka receptor , there are some functional regions in that of c terminus which can regulate these subunits targeting to the cell membrane surface . while little was known whether nmda receptor ' s nr2b subunit has the similar domains 最近有一些研究报道，许多突触受体如gaba ( b )受体rl亚单位、 ka受体的kaz和glur6亚单位以及孤儿受体腿亚单位的胞内区，存在有影响受体运输到细胞膜的功能区，但是尚未有对于nmda受体的nrz亚单位膜运输的报道。
The intracellular domain has four distinct regions : the ram domain , the ankyrin repeats , a transcriptional activator domain ( tad ) and the pest ( proline - , glutamate - , serine - , threonine - rich ) sequence . two nuclear localisation sequences are present prior to and following the ankyrin repeats 释放的胞内区不经其它信号转导分子的作用可直接进核，与dna结合蛋白rbp - j相互作用并激活下游基因如果蝇的e ( spl ) ( enhancerofsplit )复合体及哺乳类的hes ( hairyandenhancerofsplit )家族基因。
A change in functional properties of the nmda receptors has been invoked as a potential mechanism contributing to the loss of synaptic plasticity during brain maturation . from this , it is important to well understand the structural and functional diversity of nmda receptors in relation to nmda receptor subunit composition and spatial distribution at excitatory synaptic sites during development 近几年来，在哺乳动物中枢神经系统中，对离子型谷氨酸受体如何定位到兴浙江大学医学院硕士论文nrzb亚单位的c末端胞内区影响n协da受体装配、运钧以及表面表达的分子机制奋性突触的研究有了长足的发展。
Presents the use of ice thermal storage technology in public buildings , the proper collocation and control of ice - coils , base - load refrigerating machines , dual - condition refrigerating machines , plate heat exchangers and circulating pumps , and the air conditioning system design when excess heat exists in inner zone 摘要介绍了冰蓄冷技术在大型公共建筑中的应用，冰盘管蓄冰槽、基载主机、双工况主机、板式换热器和各种循环水泵的合理配置和控制要求及内区有余热时的空调系统设计。
Kyot2 lacked two lim domains from the c terminus and had a frameshift in the last exon , creating the rbp - j - binding region in the c terminus . kyotl had a negligible level of interaction with rbp - j . the binding site of kyot2 on rbp - j overlaps those of ramic and kyot2 repressed the rbp - j mediated transcriptional activation by ramic by competing with them for binding to rbp - j 在肌肉母细胞系czc12内过表达kyoth时可阻断转录激活物notch胞内区或ebnaz对rbp依赖性启动子的转录激活作用，这种阻断作用呈剂量依赖性，提示kyoth可与notch胞内区或ebnaz竞争rbp j上的结合位点，从而抑制二者的转录激活活性
Internal waves are a kind of bridge relating the diapycnal mechanical mixing to external sources of mechanical energy : first , internal waves are driven by wind stress and barotropic tide so that large amount of mechanical energy are transported to abyssal ocean with propagation of internal waves ; second , the mechanical energy can directly be cascaded to mixing through instability and breaking of internal waves 内波是外界提供的机械能与混合之间联系的桥梁之一，一方面风和潮汐通过激发内波，将能量向深海和大洋内区传递，另一方面，内波的不稳定和破碎直接将机械能串级到小尺度湍流混合中去。开展倾斜地形上内波的传播以及内潮的产生等方面的研究对海洋混合过程的参数化以及混合对大洋环流的影响等方面的研究具有重要的科学意义。
Takes several energy saving measures for air conditioning system , nick a large capacity centrifugal chillers working with variable frequency nil capacity chillers , variable frequency and variable flow control on secondary pump water systems , cooling tower for four - pipe water system in winter , fan - coil unit for commercial peripheral zones aid all - air systems for interior zones , variable frequency control on supply and exhaust air fain , enthalpy control on fresh air cooling in winter and intermediate season 采用了多项空调节能措施：大冷量离心冷水机组搭配变频小冷量机组，二次泵变频变流量空调水系统，四管制风机盘管冬季用冷却塔换冷供冷设计，商业外区风机盘管、内区全空气空调系统，送风机、排风机变频控制，过渡季、冬季利用室外新风通风降温的焓值控制设计。
