Learning is gaining and development of experiences ( behavioral habits , perception , thought ) ; memory is keeping and reappearance of experience . rescently , more and more studies have been focus on the effect of dopamine and its receptors on learning and memory 学习是指经验(行为、习惯、感知、思维)的获得和发展，记忆是指经验的保存和再现。近年来多巴胺及其受体对学习记忆的作用及其机制已引起广泛注意。
The rapid advances over the past decades in molecular biology led to new ideas and methods to investigate the mechanism of depression , which enlarged the views of fields from neurological transmitters and related receptors to post - receptor signal transduction levels 分子生物学的飞速发展为认识抑郁症的本质提供了新思路、新手段,使人们对抑郁症的研究从神经递质及其受体水平深入到受体后信号传导等领域。
Stem ce11 factor is a multipotent cytokine which is found in recent years , fol1owing research in vitro and in vivo found that scf and its receptors have familiar regu1ation function in mature brain with in embryo and developing period 干细胞因子是近年来发现的一种多功能细胞因子。近年来研究发现，干细胞因子（ stemcellfactor ， scf ）及其受体对胚胎期及成年后神经系统生长发育起调控作用，但其作用机制尚不明了。
The thesis first reviewed the recent progress in the study of three kinds of inflammatory cytokines ( il - 1 , il - 6 and tnf - a ) and their receptors . and then in two parts including four experiments , we made a series of studies about inflammatory cytokine receptors 本论文首先回顾了近年来三种炎性细胞因子( il - 1 、 il - 6和tnf - a )及其受体在脑内分布和表达的研究进展后，分两大部分四个实验，以炎性细胞因子受体作为对象进行了一系列观察和研究。
These interactions are primarily dependent upon the coordinated actions of ovarian progesterone and estrogen , moreover , many other factors , such as growth factors , cytokines , ecm , adhension molecules , oligosaccharides and proteases , regarded as local mediators , endometrium and embryo have also expressed some specific receptors , via intracellular signal transduction chains and express some key genes , making receptivity of the uterus and synchronized development of the embryo to the blastocyst stage 成功的植入是处于接受态的子宫内膜和具有侵入性的胚胎间的同步协调反应。植入过程受多种生长因子及其受体、细胞因子、粘附分子、蛋白水解酶、寡糖等的精细调控，通过胞内信号转导及关键基因的表达使子宫内膜发生一系列复杂变化。
Samples were taken from nonpregnant , pregnant and cultured endometrium cell , with using immunohistochemical staining , western - blot methods . to better understand this interaction , we further characterized the expression patterns of egfr messenger rnas in the mouse uterus on days 1 to 8 of pregnancy . in the present study , we found : two isofonns of non - phospho mapk was generally equally expressed in the nonpregnant and pregnant mice endometrium , and little difference among them 本研究以未孕及早孕小鼠( d1 ? d8 )的子宫内膜和培养的d4子宫内膜为样品，应用免疫组织化学、 western - blot等方法，检测了小鼠胚胎植入前后子宫内膜erk1 / erk2的表达部位及水平；用rt - pcr方法检测了egf及其受体egfr的表达情况；对培养的d4子宫内膜以le ~ y寡糖抗体阻断，观察了其对活性型mapk表达的影响。
Our research were divided into four parts : ( 1 ) behavioral and electrophysiological study on executive control of pfc in the macaca mulatas ; ( 2 ) the pet study on executive control of pfc in the macaca mulatas ; ( 3 ) the effects of amino acid neurotransmitters and their receptors on executive control of pfc in the macaca mulatas and rats ; ( 4 ) ultrastructural study on executive control of pfc in rats 三、氨基酸类神经递质及其受体在前额叶执行控制中的作用及机制研究vll1 .注射bmi 、 gaba 、 glu和mk一801到pfc ，均能不同程度地干扰go / nog 。任务的正确执行，增加反应时范围和错误率，表明执行控制是由中枢神经系统多种神经递质共同参与完成。
Most of mapk upstream molecules are the molecular marker of the receptivity of endometrium during implantation period , for instance , evidence suggests egf and its receptor egfr may play a role in rendering the endometrium receptive to embryo implantation . the temporal and spatial expression of ley oligosaccharide in the uterus suggests that this factor may be involved in cell - cell communication between the uterus and blastocyst during implantation period 在植入期的子宫内膜， mapks的上游信号分子大多是其接受态的标志分子，如egf及其受体egfr ，可作为胚泡与子宫内膜间的信息传递物质，代替雌激素促进子宫上皮细胞分化、增生，诱导胚胎着床。
In this study , we use immunohistochemistry , electron microscope , cell culture , image analysis , mtt method and radioimmunoassay to study the localization , varies of quantitation , and possible frictions of 5 - ht and subtype of 5 - htr in human placenta . the results were as follows : 1 本研究用免疫组织化学、免疫电镜、细胞培养、图象分析、 mtt法和放射免疫等技术对5 -羟色胺及其受体亚型在胎盘绒毛中的细胞定位及对滋养层细胞增殖和激素分泌的影响进行了初步的探讨，其结果如下： 1
Background : ghrelin is a 28 - amino acid endogenous peptide recently identified in the secretory granules of x / a - like cells in the rat stomach , which can act on the growth hormone secretagogue receptor to accelerate the secretion of growth hormone . it was identified that ghrelin - immunoreactive cell and its receptor localize in areas of brain , such as hypothalamus ( pvn , arc ) , hippocampus , adenohypophysis and so on . motilin is a 22 - amino acid peptide secreted from the upper part of the small intestine , which regulates the interdigestive motility of gastric 背景资料： ghrelin是新发现的由28个氨基酸组成的内源性脑肠肽，由胃部泌酸腺x / a样内分泌细胞分泌， ghrelin免疫活性神经元及其受体在中枢神经系统中如下丘脑室旁核( paraventricularneucleus ， pvn ) 、弓状核( arcuatenucleus ， arc ) 、海马区及腺垂体等均有不同浓度的分布，可与生长素促泌物受体( growthhormonesecretagoguereceptor ， ghsr )结合促进生长素( growthhormone ， gh )分泌。
