In most affected individuals , cgg repeats are massively expanded over 200 repeats ( full mutation ) and become abnormally h ypermethylated , w hich r esult i n t he s ilence o f t he fmr1 gene 全突变患者cgg重复次数可达n 200 ，其fmr1基因的cgg重复区域本身及其附近的cpg岛发生异常甲基化，引起基因关闭，而fmr1基因产物fmrp的缺乏，导致脆性x综合征。
At the launch of the epigenome project on tuesday , the group also released the results of a large pilot project that give " definitive proof " that dna methylation patterns are tissue specific , says beck 甲基化是主要发生在在胞嘧啶(组成dna的四个基或字母之)的一个自然过程.当一个甲基群被加到一个基因的促进者区域( -引发基因被表现的系列- )的胞嘧啶上时基因就被关闭了。
The sulfomethylated copolymer can increase the fluidity of cement paste 20 % , and it has longer time retarding performance . the influence of the molecular weight of copolymer and the proportion of monomers on the property of sulfomethylated copolymer has been discussed 通过对酰胺基团的磺甲基化改性得到初始流动度提高了20的改性产物，且改性产物具有较长时间的缓凝性。
Research in recent years showed that dna methylation play a role in regulating gene expression , but the assay on relationship between dna methylation and flowering were mainly focused on model plants such as arabidopsis 近年来的研究表明， dna甲基化在植物基因表达调控中发挥重要的作用，但有关甲基化与植物开花关系的研究只是在拟南芥等模式植物上进行的较多，其它植物上的报道还很少。
Since the methylation process takes place even before a malignant tumor can be detected with normal exams , the discovery may help doctors detect cancer earlier , and eventually find a way to treat it by suppressing the cause behind the methylation process 由于在常规检查发现恶性肿瘤之前甲基化进程就已经开始，这项发现可能会帮助医生更早的发现肿瘤，并通过排除甲基化背后的因素最终找到治疗的方法。
In the synthesizing process , the ph value in hydroxymethylated stage , the reaction time , temperature and the moore ratio of sodium bisulfate to melamine in the sulfonated stage , and die ph value in the condensation stage , are important factors influencing on the performance of jd 在合成过程中，羟甲基化阶段的ph值，磺化阶段的ph值、时间、温度和投料摩尔比，缩合阶段的ph值等对减水剂性能影响显著。
