Effect of hypoxia on expression of c - fos in neurons of cerebrum from rats ' embryos and protective role of angelica sinensis 纳洛酮对减轻全脑缺血再灌注后神经元损伤作用的实验研究
Effect of tetrandrine on the functional changes in calcium channels induced by anoxia in cerebral cortical neurons acutely isolated from rats 纳洛酮对大鼠局灶性脑缺血再灌注损伤的保护作用
The effect of naloxone on fentanyl - induced changes in striatal ascorbic acid uric acid dopamine and its metabolic release in rats 纳洛酮对芬太尼引起的大鼠纹状体抗坏血酸尿酸多巴胺及其代谢产物释放的影响
Relationship between the protective effect of sodium oxybate on neuronal damage induced by hypoxia - reoxygenation and gabaa receptor in primary cultured rat cortical neurons 脑室注射纳洛酮对大鼠脑缺血再灌注损伤的保护作用
The nociceptin - induced current was not affected by tetrodotoxin ( ttx ; 1 um ; n = 4 ) and also by a non - specific opioid receptor antagonist , naloxone ( 1 um ; n = 4 ) 灌流m （ tetrodotoxm ； lqm ； n 4 ）和纳洛酮（阿片类受体的非特异性桔抗剂； l卜n 4 ）均对nociceptin诱致的外向电流也不产生任何作用。
Therefore , the purpose of the present study was to determine whether the opioid receptor and its downstream pathway are involved in the cardiovascular effect of il - 2 and whether the effect of il - 2 under physiological or pathological conditions is changed . 1 effect of interieukin - 2 on contraction of enzymatically isolated ventricular myocytes cytokines play significant roles in some cardiovascular disorders , but direct myocardial effects of cytokines remain to be elucidated （ 4 ）非选择性阿片受体阻断剂纳洛酮（ nal ） （ 10nmol几）和选择性x阿片受体阻断剂norbni （ 10nmol l ）预处理后，可阻断il 2对心室肌细胞收缩的抑制作用，而选择性5阿片受体阻断剂纳曲呗跺（ nti ）门卜r口）不能阻断此作用。
Injected group , 0 . 1 % saccharin ( 1 . 5 ~ 2ml / rat , in 5min ) intraoral infused group and cta group . the expression of endogenous leucin - enkephalin ( lek ) in the rat brain was observed and 5 parts of the thalamus including laterodorsal thalamic nucleus ( ld ) , lateral part of mediodorsal thalamic nucleus ( mdl ) , ventroposterolateral thalamic nucleus ( vpl ) , ventroposteromedial thalamic nucleus ( vpm ) and reticular thalamic nucleus ( rt ) were comparatively researched before and after the acquisition of cta applying lek - immunocytochemistry . in behavioral experiment , 18 adult male sd rats were divided into normal cta group ( control ) and 2 naloxone i . p 为探讨cta形成过程中enk的作用，本实验用成年雄性sd大鼠35只，分为空白对照组、生理盐水( 2体重)腹腔注射组、 0 . 15mlicl溶液( 2体重)腹腔注射组、 0 . 1糖精溶液口腔灌流组( 1 . 5 - 2ml只， 5min )和cta建立组，采用免疫细胞化学方法，观察了亮脑啡肽( lek )阳性神经元在大鼠脑内的分布情况，并比较了各组大鼠丘脑外侧背核( ld ) 、丘脑内侧背核外侧部( mdl ) 、丘脑腹后外侧核( vpl ) 、丘脑腹后内侧核( vpm )以及丘脑网状核( rt )等5个脑区内lek表达水平的差异；另外将成年雄性sd大鼠18只，分为正常cta建立组以及在cta建立前或cta建立后阿片受体拮抗剂纳洛酮( 2mg kg体重)腹腔注射组，对内源性阿片样物质对于cta建立和保持的影响进行了行为学研究。
