Hepatocellular carcinoma is the fifth most common cancer globally with over 600 , 000 new cases diagnosed each year . the disease is the leading cause of death in patients with cirrhosis 全球范围内，肝细胞癌的发病率为第五位，每年有60万的新发病例。在肝硬化的病人，肝细胞癌为首位致死原因。
Methods . thirty - eight candidates for lt with hepatitis c virus ( hcv ) cirrhosis and hcc were studied . gene expression ( gexp ) analysis of tumor samples was performed using microarrays 对于小肝癌( hcc )的患者而言，肝移植是一种根治疗法。由于缺乏预测进展和复发的肿瘤标志物那些有可能被治疗的更高阶段的肝细胞癌的患者被拒绝用肝移植疗法。
" presently available systemic therapies for hepatocellular carcinoma have no documented survival benefit , " he said . " our study establishes sorafenib as the new reference standard for systemic therapy in these patients . 他说： “现在所应用的肝细胞癌全身治疗对于生存率没有任何效果，我们的研究为这类病人建立了以索拉非尼为新参考标准的全身治疗方案。 ”
Increased speed combined with thin slice collimation obviously improves the spatial and temporal resolution , which provides a higher sensitivity in the detection of liver lesions , particularly for the hepatocellular cancer ( hcc ) in patients with cirrhosis 加快的扫描速度与薄层结合显著提高了空间和时间分辨率，从而提供了对肝脏病变，尤其是患有肝硬化的肝细胞癌患者更高的诊断敏感性。
