Expression of hypoxia - inducible factor 1 alpha hif - 1 and its relationship with tumor angiogenesis in human breast carcinoma 在乳腺癌组织中的表达及其与肿瘤血管形成的关系
Expression of cox - 2 in gastric carcinomas and its relationship to tumor angiogenesis and micrometastasis in peripheral blood 2的表达与肿瘤血管生成及周围静脉血微转移的关系
J591 may work in a new way , taking anti - angiogenic therapy to the next leel by directly targeting psma on the cells of the tumor blood essels and then zooming in for the kill 而j591抗体作用的机制不同上述方法，它通过直接针对肿瘤血管细胞表面的psma起作用来治疗肿瘤。
It enhances thl cell growth , inhibits th2 cell growth and enhances the cytotoxic activity of cd8 + t cells and nk cells as well as stimulates b cell igg2a production 它能促进mhci类和11类分子的表达，促进thl和ctl的分化及b细胞iggza的产生，增强nk活性和ctl活性，抑制肿瘤血管的生成。
In studies of mice , the researchers found that angiogenesis inhibitors decreased the diameters of tumor blood vessels and made them less leaky , so they began to resemble normal vessels 研究人员在小鼠的身上发现，血管新生抑制剂会使肿瘤血管的管径缩小，让这些血管比较不那麽容易渗漏，而变得更像正常的血管。
Sorafenib , a novel , oral multi - kinase inhibitor , targets on serine / threonine and receptor tyrosine kinases of the tumor cells and vasculature ; blocks the signal transconduction and inhibits tumor growth 摘要索拉非尼是首个口服多激酶抑制药，靶向作用于肿瘤细胞和肿瘤血管上的丝氨酸和（或）苏氨酸及受体酪氨酸激酶，阻断信号传导，抑制肿瘤生长。
Conclusion with the development of molecular biology and the exploitation of antiangiogenesis , it is of great importance for glioma which is characterized by vascular proliferation to study deeply on the antiangiogenesis therapy 结论随着分子生物学的发展，肿瘤血管抑制剂的不断开发和研究，对于脑胶质瘤这一血管增生极为突出的肿瘤，深入研究抗血管治疗具有重要意义。
Emerging evidence indicated that integrin a5 1 might play a role in these processes by influencing the interaction between tumor cells and the extracellular matrix , promoting tumor angiogenesis and regulating apoptosis of cancer cells 而这种作用可能是通过影响肿瘤细胞与细胞外基质的黏附、细胞外基质的水解、诱导肿瘤血管的生成、调节肿瘤细胞的凋亡等作用而实现的。
As a proteasome inhibitor , bortezomib has shown inhibition on cell proliferation , inducing cell apoptosis , inhibition of cell adhension and inhibition of tumor angiogenesis for multiple myeloma cells 摘要硼替佐米作为一种蛋白酶抑制剂，对多发性骨髓瘤细胞表现出抑制细胞生长、诱导肿瘤细胞凋亡、抑制细胞粘附、抑制肿瘤血管生成等作用，同时对血液系统其他恶性肿瘤具有显著的作用。
Psma has been an attractie target for cancer drug deelopment because it is not only present in high amounts in prostate cancers but it also is the only known molecular target present on tumor blood essels but not normal blood essels Psma之所以成为肿瘤治疗药物研发的吸引人的靶标是因为它不仅只在前列腺癌中大量出现，而且它是唯一的只存在于肿瘤血管的分子靶标，而不存在于正常血管组织。
