This response ranges from mild cutaneous reactions , such as pruritus and urticaria , to life threatening cardiovascular collapse 反应包括较轻的皮肤反应如瘙痒和荨麻疹，严重者则危及生命，如心血管性虚脱。
In most cases of chronic urticaria , an underlying trigger is not found . hodgkin ' s disease may be accompanied by urticaria . cold urticaria with cryoglobulinemia is seen in multiple myeloma 在大多数慢性荨麻疹患者，找不到触发原因。霍杰金氏病可伴有荨麻疹；冷球蛋白血症引起的荨麻疹见于多发性骨髓瘤。
New york ( reuters health ) may 21 - rupatadine is significantly better than placebo for the treatment of chronic idiopathic urticaria , spanish researchers report in the may issue of allergy 纽约路透社健康栏目5月21日报道，研究者发布在过敏症5月刊上的研究表明，卢帕他定治疗慢性特发性荨麻疹显著优于安慰剂。
Skin nick disease namely artificial urticaria , can happen at any ages , children is not exceptional also , often first skin sao itchs or glowing , catch via scratching after delimit gently or chafing , appear linear wind is round 皮肤划痕症即人工荨麻疹，可发生于任何年龄，儿童也不例外，往往先有皮肤瘙痒或灼热，经搔抓轻划或摩擦后，出现线状风团。
Signs and symptoms usually develop within minutes and may include tingling in the mouth , hives , swelling of the lips , face , tongue and throat , wheezing or breathing difficulties , dizziness , abdominal pain , diarrhea , nausea or vomiting 过敏的症状与体征经常在数分钟内产生，常见的症状有口腔麻刺感，荨麻疹，脸、口唇、舌头以及咽喉肿胀，出现哮鸣音或呼吸困难，头晕、腹痛、腹泻、恶心或呕吐。
