actinomycin造句

• Actinomycin is a complex molecule that intercalates DNA and prevents RNA synthesis.
• The systematic name of this enzyme class is "'actinomycin lactonohydrolase " '.
• Actinomycin-D is believed to produce its cytotoxic effects by binding DNA and inhibiting RNA synthesis.
• Actinomycin D and its fluorescent derivative, 7-aminoactinomycin D ( 7-AAD ), are used as stains in microscopy and flow cytometry applications.
• Animal studies have shown actinomycin-D is corrosive to skin, irritating to the eyes and mucous membranes of the respiratory tract and highly toxic by the oral route.
• He is known for the discovery of actinomycin, and the development of the industrial production by fermentation of many natural products, including cyanocobalamin, the avermectins, and other important antibiotics.
• It was at Rutgers that Waksman's team discovered several antibiotics, including actinomycin, clavacin, streptothricin, streptomycin, grisein, neomycin, fradicin, candicidin, candidin, and others.
• Viral RdRPs were discovered in the early 1960s from studies on mengovirus and polio virus when it was observed that these viruses were not sensitive to actinomycin D, a drug that inhibits cellular DNA-directed RNA synthesis.
• Through the sequential use of two drugs, methotrexate and actinomycin-D, cures were achieved in up to 90 percent of women with choriocarcinoma who were treated by 1972; 90 percent of those who were not treated died within a year.
• ""'Streptomyces flavovirens " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from soil . " Streptomyces flavovirens " produces the actinomycin complex and mureidomycin.
• At present, treatment with single-agent methotrexate is recommended for low-risk disease, while intense combination regimens including EMACO ( etoposide, methotrexate, actinomycin D, cyclosphosphamide and vincristine ( Oncovin ) are recommended for intermediate or high-risk disease.
• ""'Streptomyces showdoensis " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from soil in Japan . " Streptomyces showdoensis " produces terferol, actinomycin and showdomycin.
• ""'Streptomyces flaveolus " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from soil . " Streptomyces flaveolus " produces L-isoleucine, actinomycin J and tirandamycin.
• ""'Streptomyces sindenensis " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from soil in Japan . " Streptomyces sindenensis " produces actinomycin-D and the amicetin complex
• It was at Rutgers that Selman Waksman ( 1888 1973 ) discovered several antibiotics, including actinomycin, clavacin, streptothricin, grisein, neomycin, Albert Schatz ( 1920 2005 ), discovered streptomycin a versatile antibiotic that was to be the first applied to cure tuberculosis.
• The whole of replication occurs within the host cell cytoplasm and infection can even happen in cells that do not contain a nucleus ( known as enucleated cells ) and those treated with actinomycin D ( this antibiotic would inhibit viral replication if this occurred in the nucleus .)
• One study which did address this topic used flow cytometry or elutriation of synchronized cells treated with actinomycin D1, camptothecin, or aphidicolin, each of which had been documented to exert its effects in a particular phase of the cell cycle . which the later papers reference.
• ""'Streptomyces michiganensis " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from soil in the United States . " Streptomyces michiganensis " produces actinomycin X, antipain and mitomycin.
• ""'Streptomyces parvus " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from garden soil . " Streptomyces parvus " produces the actinomycin C complex, arylomycin A5, arylomycin A6 and actinomycin D.
• ""'Streptomyces parvus " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from garden soil . " Streptomyces parvus " produces the actinomycin C complex, arylomycin A5, arylomycin A6 and actinomycin D.