シトクロムp450造句

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cytochrome p450 CYP3A4 is a member of the cytochrome P450 family of oxidizing enzymes. For example, it affects heme and cytochrome P450, and decreases their effectiveness. Individual cytochrome P450-2D6 e...
cytochrome p450 1a2 "' Cytochrome P450 1A2 "'( abbreviated "'CYP1A2 "'), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body. Ciprofloxacin ...
cytochrome p450 2c9 Its leaves are known to contain 6-Hydroxyflavone, one of the chemical compounds that is a noncompetitive inhibitor of the protein cytochrome P450 2C9.
cytochrome p450 2d6 The majority of flecainide is eliminated by the kidneys, with the remainder metabolized by the cytochrome P450 2D6 isoenzyme in the liver. Quinidine sulfate, as a metabolic inhibitor, " in...
cytochrome p450 2e1 Glycidamide is naturally formed by oxidation of acrylamide by cytochrome P450 2E1 ( CYP2E1 ). These include cytochrome P450 2E1 ( CYP2E1 ), quinine oxidoreductase ( NQ01 ), GSH, and myelop...
cytochrome p450 3a4 Ziprasidone is hepatically metabolized by aldehyde oxidase; minor metabolism occurs via cytochrome P450 3A4 ( CYP3A4 ). Terfenadine is a prodrug, generally completely metabolized to the ac...
cytochrome p450 enzyme system Because of the dual elimination routes of flecainide and its tendency to decrease cytochrome P450 enzyme system. About 20 percent of dofetilide is metabolized in the liver via the CYP3A4 i...
cytochrome p450 eryf Cytochrome P450 eryF ( CYP107A1 ) originally from the bacterium is responsible for the biosynthesis of the antibiotic by C6-hydroxylation of the macrolide 6-deoxyerythronolide B.
cytochrome p450 family CYP3A4 is a member of the cytochrome P450 family of oxidizing enzymes. The CYP3A group of enzymes are the most abundantly expressed members of the cytochrome P450 family in liver. It is th...
cytochrome p450 gene The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. This gene is part of a cluste...
cytochrome p450 monooxygenase AveE has cytochrome P450 monooxygenase activity and facilitates the furan ring formation between C6 and C8. This intermediate is subsequently converted by a benzophenone 32-hydroxylase, a ...
cytochrome p450 oxidase Aldosterone synthase is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone. "' Paracetamol "'( acetaminophen, APAP ) is converted into the hepat...
cytochrome p450 reductase For the electron transfer a conformational change occurs that triggers interaction of the P450 with the NADPH cytochrome P450 reductase. Eukaryotic microsomal P450 enzymes and some bacteri...
cytochrome p450 superfamily CYP1A2 is a member of the cytochrome P450 superfamily of enzymes. The gene encodes a member of the cytochrome P450 superfamily of enzymes. Aldosterone synthase is a member of the cytochrom...
cytochrome p450 system Pantoprazole is metabolized in the liver by the cytochrome P450 system. There is no metabolic involvement of the hepatic cytochrome P450 system. The metabolism of metaxalone involves the l...
nadph cytochrome p450 reductase For the electron transfer a conformational change occurs that triggers interaction of the P450 with the NADPH cytochrome P450 reductase. Breaking of hydrogen bonds between S128-N287, S128-...
p450 The biosynthesis of atropine starting from P450 enzyme forming hyoscyamine aldehyde. Pentamidine is primarily metabolized by Cytochrome P450 enzymes in the liver. Pantoprazole is metaboliz...
p450 2d6 LKM-1 antibodies associated with autoimmune chronic active hepatitis recognize P450 2D6, a cytochrome P450 mono-oxygenase. The majority of flecainide is eliminated by the kidneys, with the...
p450 enzyme system Because of the dual elimination routes of flecainide and its tendency to decrease cytochrome P450 enzyme system. About 20 percent of dofetilide is metabolized in the liver via the CYP3A4 i...
p450 oxidase Aldosterone synthase is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone. "' Paracetamol "'( acetaminophen, APAP ) is converted into the hepat...
p450 oxidoreductase "' Cytochrome P450 reductase "'(; also known as NADPH : ferrihemoprotein oxidoreductase, NADPH : hemoprotein oxidoreductase, NADPH : P450 oxidoreductase, P450 reductase, "'POR "', CPR, CYP...
p450 system Pantoprazole is metabolized in the liver by the cytochrome P450 system. There is no metabolic involvement of the hepatic cytochrome P450 system. The metabolism of metaxalone involves the l...
p450酶系在离体实验中未发现本品经细胞色素P450酶系统代谢。细胞色素P450酶系统催化内源性和外源性化合物的代谢。 P450酶系成员之一的CYP2C19，负责代谢抗癫痫药物美芬妥英（Mephenytoin）。资料显示，溴夫定不会诱导或抑制肝细胞色素P450酶系统。离体研究证实喹硫平的主要代谢酶为细胞色素P450酶系统的CYP3A4。代谢与排泄：埃索美拉唑完全经细胞色素P45...
细胞色素p450 本品和细胞色素P4503A系统亲和力高。本品不通过细胞色素P4502D6代谢。细胞色素P450并不参与维替泊芬的代谢。 7.硝苯地平通过细胞色素P4503A4系统代谢消除。尤其，本品对细胞色素P4503A4抑制作用广而强。非那雄胺主要在细胞色素P4503A4酶系的催化下代谢。波生坦在肝脏中被细胞色素P450同工酶CYP3A4和CYP2C9代谢。没有进行研究观察培...
细胞色素p450同工酶一些细胞色素P450同工酶与遗传多态性有关。波生坦在肝脏中被细胞色素P450同工酶CYP3A4和CYP2C9代谢。一种药物代谢涉及到一种以上的细胞色素P450同工酶。没有进行研究观察培美曲塞对细胞色素P450同工酶的影响。整个肠道粘膜内，细胞色素P450同工酶存在有不同的数量。 NADPH依赖的肝酶系统（包括细胞色素P450同工酶）不参与维替泊芬代谢。 3.本药对经...