A method for preparation of antithrombin ( at - ) concentrated from human plasma ' s fraction has been described . after preliminary treatment of plasma with the cold ethanol , the isolation of at - iii from the precipitate was performed by affinity chromatography on heparin - sepharose cl - 6b ; desalted by dialysis and concentrated 从人体血浆中提取较高纯度的抗凝血酶( at - )的,通过低温乙醇处理血浆,得到的沉淀经肝素-琼脂糖两次亲和层析,并透析、浓缩获得at -的初品。
Antithrombin (AT) is a small protein molecule that inactivates several enzymes of the coagulation system. Antithrombin is a glycoprotein produced by the liver and consists of 432 amino acids.