ldlr中文是什么意思

• 低密度脂蛋白受体

• ldh酶    lactate déshydrogénaseldh
• ldh    ldh酶乳酸脱氢酶
• ldpc    低密度奇偶检查码
• ld3    集装器
• ldtv    ldtv (low definition tv)低清晰度电视[机]
• lcs    脑脊液
• lcr    脑脊液
• le 13e guerrier    杀战风云

• This inhibition redirects the LDLR to the lysosome instead.
• In addition, LDLR modulation is associated with early atherosclerosis-related lymphatic dysfunction.
• When PCSK9 binds to an LDLR, the receptor is destroyed along with the LDL particle.
• Reduced LDLR levels result in decreased metabolism of LDL-particles, which could lead to hypercholesterolemia.
• The PCSK9 antisense oligonucleotide increases expression of the LDLR and decreases circulating total cholesterol levels in mice.
• Naringenin seems to protect LDLR-deficient mice from the obesity effects of a high-fat diet.
• At neutral pH the LDLR is in an extended linear conformation and can bind ligands ( PCSK9 ).
• Tva contains sequences related to the ligand binding region of low-density lipoprotein receptors ( LDLR ).
• The mutations increase its protease activity, reducing LDLR levels and preventing the uptake of cholesterol into the cells.
• This protein plays a major regulatory role in cholesterol homeostasis, mainly by reducing LDLR levels on the plasma membrane.