- 低密度脂蛋白受体
ldlr中文什么意思
- 低密度脂蛋白受体
例句与用法
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- This inhibition redirects the LDLR to the lysosome instead.
- In addition, LDLR modulation is associated with early atherosclerosis-related lymphatic dysfunction.
- When PCSK9 binds to an LDLR, the receptor is destroyed along with the LDL particle.
- Reduced LDLR levels result in decreased metabolism of LDL-particles, which could lead to hypercholesterolemia.
- The PCSK9 antisense oligonucleotide increases expression of the LDLR and decreases circulating total cholesterol levels in mice.
- Naringenin seems to protect LDLR-deficient mice from the obesity effects of a high-fat diet.
- At neutral pH the LDLR is in an extended linear conformation and can bind ligands ( PCSK9 ).
- Tva contains sequences related to the ligand binding region of low-density lipoprotein receptors ( LDLR ).
- The mutations increase its protease activity, reducing LDLR levels and preventing the uptake of cholesterol into the cells.
- This protein plays a major regulatory role in cholesterol homeostasis, mainly by reducing LDLR levels on the plasma membrane.