Integrins recognize cues encoded by the extra - cellular matrix and convert them into complex biochemical signals that control the behavior of cells 它通过介导复杂的信号通路,将细胞外信息内传,调控细胞的生命活动。
15 heinrich r , neel b g , rapoport t a . mathematical models of protein kinase signal transduction . mol . cell , 2002 , 9 : 957 - 970 这些结果有助于设计相关的生物实验,进一步研究细胞的jak - stat信号通路的对外界影响的变化。
According to the result from blast , apoptin maybe take part in the signal pathway of programmed cell death with activity of enzyme 这预示着凋亡素可能是通过发挥某种酶的作用来参与到细胞凋亡信号通路中,最终诱发肿瘤细胞凋亡的。
Axudl is a novel human gene induced by axin1 in wnt signal transduction passway and identified in human colon - cancer cell Axud1 ( axin1up - regulated )基因是近年来在人类结肠癌细胞中鉴定出的受wnt信号通路中的轴蛋白axin1上调表达的基因。
Conclusion inhibition of the expression and signaling pathway of steroid receptor coactivators may he effective for breast cancer prevention and treatment 结论抑制类固醇受体辅活化因子的表达及其相关信号通路可能是今后预防和治疗乳腺癌的一种有效途径。
The researchers are investigating genes and proteins of the influenza viruses of swine , horses and birds to see how they activate downstream cellular signalling pathways 研究者正在调查猪,马和禽流感病毒的基因和蛋白,看它们是如何活化后续的细胞信号通路。
In this paper , we review the recent research concerning the integrin activation and integrin signaling , as well as their cooperation with receptor protein tyrosine kinases 本文综述了整合蛋白的活化过程、信号转导过程及其与生长因子受体信号通路相互关联研究的最新进展。
The mechanical actions d shear a can be detected by mechanosensors on ecs and converted into specific signaling pathways to mediate the structural and functional remodeling 血管内皮细胞能感受血流机械力的变化,通过激活相应的信号通路调节血管内皮和平滑肌的结构和功能。
We hope to elucidate the characteristics of injury induced by nmda in vitro and find potential important targets for therapeutic invention for cerebral ischemia . 1 希望通过本研究,能够阐明体外nmda损伤特点及发现抗脑缺血新药的途径;并且,为今后药物干预兴奋性氨基酸信号通路打下必要的基础。
Correspondingly , the egf binding affinity of surface egfr and the tyrosine auto - phosphorylation of immuno - precipitated egfr were also enhanced in gntv - s / h7721 cells and reduced in gntv - as / h7721 cells Egfr的信号通路主要有两条,一是ras - raf - mek一mapk经典途径,另一条是新发现的pi一3k一pkb途径。