O . osmm of snp could activate the pbmc , while above 0 . 5 mm of snp could significantly induce pbmc necrosis , nevertheless , the higher concentration of snp could not induce significant change of cytokine production , cell cycle , and ratio of pbmc subsets 0刀smm的swh有活化pbmc的作用，大于0 sinm的snp会大量诱导pbmc的坏死，但对细胞因子、细胞周期、细胞亚群的比例均影响不大。
In the present study , using the conventional whole - cell mode and perforated whole - cell patch claxnp mode , the role of intracellular and extrce1lular calcium in snp - induced increase of ik ( . . ) were investigated . l 我们分别应用传统全细胞模式和穿孔模式的膜片钳技术，研究了细胞内外钙离于在s p诱导人h ）增加中的作用，进而阐明no引起豚鼠胃窦环行肌舒张的离子机制。
Began to increase after 4 . 2 l 2 . 9 seconds ( the cel1s were superfused with l00 u m snp bath solution ) at 60 mv l0 . 6i4 . 3 seconds at peak , and resumed after 272 . 3 i 87 . 0 seconds ( wash out with physiological salt solution ) 当平滑肌细胞用含100uh4snp生理盐水灌流并同样去极化至60mv时， ik （ m ）平均在4二士295开始增加， 10石土4 3s达到高峰，当用生理盐水灌流2后平均297士87
As companies began to apply for patents on great swathes of genetic markers for these traits , especially the tiny variations called snps , top institutions and pharmaceuticals companies became so concerned that they set up the snp consortium 在研究人员还没有排列出人类染色体前，这些人就已经开始鉴别基因的变异，以便让医生可以诊断一个特定的病人是不是对患上心脏病特别敏感，或者说，是不是能有一种特效药对他们起作用。
Here , using stomatal analysis and laser scanning cofocal microscope techniques , we show firstly that no as the downstream intermediate of h2o2 signaling mediates aba - induced stomatal closure in viciafaba l . sodium nitroprusside ( snp , a no donor ) and h2o2 could mimic the effects of aba on stomatal closure 由aba或h _ 2o _ 2所诱导的蚕豆气孔关闭过程可部分地被no的专一清除剂c - ptio所逆转，而h _ 2o _ 2的清除剂过氧化氢酶( cat )则不能逆转no诱导的气孔关闭过程。
After extending the sequenced region tb whole control region , the sequence in han , li , wei , yao , zang ethnic groups revealed that the discrimination power of mtdna was increased greatly . the novel str and snp loci found in the region of mtdna also provide useful markers for screening test of forensic samples 对汉族、黎族、维族、瑶族、藏族群体进行序列分析结果表明，将检测区域从hvi和hvh扩大到覆盖整个控制区及其周围区域后大大提高了mtdna这一遗传标记在法庭科学领域的鉴别能力。
We transform the profile of snp into ibd profiling and use the mpisc algorithm proposed to extract snp combination with differential ibd distributions among the affected groups of sibpairs . we can generate dummy interaction network of snps based on the mined snp combinations , and further reflect the interactions among genes that are mapped by the snps and construct interaction network of genes 这些snp协作簇不仅可以定位复杂疾病相关多基因,而且反应相关基因的互作关系,可以进一步构建snp虚拟互作网络,进而映射为基因之间的互作关系,最终完成对复杂疾病互作多基因精确定位和基因互作网络构建。
