aconitate造句

• In aconitase, the Fe S cluster binds aconitate at the one Fe centre that lacks a thiolate ligand.
• The systematic name of this enzyme class is "'aconitate Delta2-Delta3-isomerase " '.
• It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle.
• Another hypothesis is that " cis "-aconitate stays bound to the enzyme while it flips from the citrate to the isocitrate mode.
• In either case, flipping " cis "-aconitate allows the dehydration and hydration steps to occur on opposite faces of the intermediate.
• Although at least one rumen organism converts trans-aconitate to acetate, other rumen organisms convert trans-aconitate to tricarballylate, which complexes with magnesium.
• Although at least one rumen organism converts trans-aconitate to acetate, other rumen organisms convert trans-aconitate to tricarballylate, which complexes with magnesium.
• The generally accepted route for itaconate is via glycolysis, tricarboxylic acid cycle, and a decarboxylation of " cis "-aconitate to itaconate via " cis "-aconitate-decarboxylase.
• The generally accepted route for itaconate is via glycolysis, tricarboxylic acid cycle, and a decarboxylation of " cis "-aconitate to itaconate via " cis "-aconitate-decarboxylase.
• One theory is that, in the rate-limiting step of the mechanism, the " cis "-aconitate is released from the enzyme, then reattached in the isocitrate mode to complete the reaction.
• These exude a range of carboxylates, including citrate, malonate and " trans "-aconitate, that act as acid phosphatase, allowing the absorption of nutrients from nutrient-poor soils, such as the phosphorus-deficient native soils of Australia.
• His-101 protonates the hydroxyl group on C3 of citrate, allowing it to leave as water, and Ser-642 concurrently abstracts the proton on C2, forming a double bond between C2 and C3, forming a " cis "-aconitate intermediate.
• To complete the reaction, the serine and histidine residues reverse their original catalytic actions : the histidine, now basic, abstracts a proton from water, priming it as a nucleophile to attack at C2, and the protonated serine is deprotonated by the " cis "-aconitate double bond to complete the hydration, producing isocitrate.
• Trans-aconitate, which accumulates in some grasses, can be a risk factor for hypomagnesemia in grazing ruminants . ( Tetany has been induced in cattle by administration of trans-aconitate and KCl, where the amount of KCl used was, by itself, insufficient to induce tetany . ) Relatively high levels of trans-aconitate have been found in several forage species on rangeland sites conducive to hypomagnesemia.
• Trans-aconitate, which accumulates in some grasses, can be a risk factor for hypomagnesemia in grazing ruminants . ( Tetany has been induced in cattle by administration of trans-aconitate and KCl, where the amount of KCl used was, by itself, insufficient to induce tetany . ) Relatively high levels of trans-aconitate have been found in several forage species on rangeland sites conducive to hypomagnesemia.
• Trans-aconitate, which accumulates in some grasses, can be a risk factor for hypomagnesemia in grazing ruminants . ( Tetany has been induced in cattle by administration of trans-aconitate and KCl, where the amount of KCl used was, by itself, insufficient to induce tetany . ) Relatively high levels of trans-aconitate have been found in several forage species on rangeland sites conducive to hypomagnesemia.