allylestrenol造句

• Allyltestosterone is the parent structure of two medically used 19-nortestosterone progestins, allylestrenol and altrenogest.
• Other progestogens including medroxyprogesterone acetate, lynestrenol, allylestrenol, dydrogesterone, and normethandrone have also been found to be effective for migraine in a high percentage of women.
• As it is lacking in a keto group at the C3 position, allylestrenol is thought to be a prodrug into 17?-allyl-19-nortestosterone ( or 17?-allylnandrolone ).
• Testosterone derivatives with low ( but potentially still significant ) androgenic activity include desogestrel, etonogestrel, gestodene, and norgestimate, while norelgestromin, noretynodrel, norgesterone, allylestrenol, and dimethisterone appear to have negligible activity.
• Allylestrenol is marketed widely throughout Europe, including in the United Kingdom ( no longer available ), Russia, and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably not in the United States or Canada.
• Although it is less potent as a progestogen relative to many other 19-nortestosterone derivatives, allylestrenol is said to be virtually devoid of androgenic, estrogenic, or glucocorticoid activity, and hence, unlike virtually all other 19-nortestosterone derivatives, appears to be a pure progestogen with similar effects to those of progesterone.