aminoimidazole造句

• The formation of 5-aminoimidazole-4-carboxyamide ribotide ( AICAR ) transformylase.
• It primarily inhibits the enzyme thymidylate synthase, but also has effects on DHFR, aminoimidazole carboxamide ribonucleotide formyltransferase and glycinamide ribonucleotide formyltransferase.
• Dehydration of FGAM by enzyme FGAM cyclase results in the closure of the imidazole ring, as 5-aminoimidazole ribonucleotide ( AIR ).
• Continuing down the pathway, the removal of the carbon skeleton of aspartate by SAICAR lyase results in 5-aminoimidazole-4-carboxamide ribonucleotide ( AICAR ).
• It is reported in literature that during the synthesis of a Coelenterazine derivative, a non-radical hydrogen abstraction was observed on a substituted aminoimidazole in a typical Sandmayer hyroxilation condition.
• For example, vertebrates have a multi-enzyme polypeptide containing the GAR synthetase, AIR synthetase and GAR transformylase modules ( GARs-AIRs-GARt; GAR : glycinamide ribonucleotide synthetase / transferase; AIR : aminoimidazole ribonucleotide synthetase ).
• Activation of AMP-activated protein kinase ( AMPK ), the cellular energy sensor, by 5-aminoimidazole-4-carboxamide ribonucleoside ( AICAR ), also markedly upregulated PRODH and increased PRODH-dependent ATP levels, further supporting its role during stress.