dach1造句

• DACH1 plays an important role in retinal and pituitary precursor cell proliferation.
• DACH1 also has other functions related to cell activity.
• DACH1 is responsible for the inhibition of cell migration.
• A ) Bioluminescent images showing the effect of DACH1 overexpression on breast cancer cells.
• DACH1 plays an important role on this precursor of cell proliferation in retinal and pituitary.
• DACH1 expression decreases when the cancer is more invasive and the level of estrogen is high.
• Dach1 regulates early progenitor cell proliferation during mammalian retinogenesis and pituitary development by directly repressing cyclin-dependent kinase inhibitors.
• Dach1 is highly expressed in the adult podocyte, with transcripts showing an approximate ten fold enrichment compared to total kidney cortex.
• DACH1 protein is able to prevent the proliferation of cancerous cells due to being a natural repressor of estrogen receptors in the normal function of mammary tissue.
• Some other processes that DACH1 protein regulates by reducing the frequency, are the transcription of a specific gene, the synthesis process of DNA and the reproduction of fibroblast cells.
• Third, Pestell defined key target genes required for breast cancer stem cell expansion in vivo including p21Cip1, c-Jun, the canonical NF-?B pathway, and the cell fate determination pathway protein DACH1 . [ 8]
• Ten days after the tail vein injection, firefly luciferase bioluminescence signals of the 4T1 / Luc cells were acquired and analysed . b ) The images showing the effect of DACH1 overexpression on lung size in mice ( left ).