endosomal造句

• It specifically targets endosomal TLR3 with good solubility and serum stability.
• Vps4p is anchored via Vps46p to the endosomal membrane.
• EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking.
• Multivesicular bodies are endosomal compartments that sort ubiquitinated membrane proteins by incorporating them into vesicles.
• Rab18 was first characterised as an endosomal protein in epithelial cells of mouse kidney and intestines.
• Certain neurodegenerative diseases such as Alzheimer's have been found to have defective endosomal trafficking.
• The SNX-BAR dimer enters the nucleation complex via direct binding or lateral movement on endosomal surface.
• The mannose receptor recycles continuously between the plasma membrane and endosomal compartments in a clathrin-dependent manner.
• This domain is buried in the late endosomal membrane and may associate with the same domain in MENTHO.
• It is localized to the endosomal compartment of the cell with the LRR region facing into the endosome.
• The domain mounts TLR 11 to the endosomal membrane and connects the LRR region to the TIR domain.
• The insulin receptor system, in contrast, appears to " diminish " the efficacy of endosomal signaling.
• Once inside the cell, the viral membrane fuses with the endosomal membrane, and the virus genome is released.
• This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body / late endosome pathway.
• It is suggested that in combination with MLN64, this protein helps regulate the flow of cholesterol through the endosomal pathway.
• ESCRT-II in turn functions downstream of ESCRT-I, a protein complex that binds to ubiquitinated endosomal cargo.
• APCs usually internalize exogenous antigens by endocytosis, but also by pinocytosis, macroautophagy, endosomal microautophagy or chaperone-mediated autophagy.
• Potential mechanisms . IFITM proteins inhibit viral membrane and cellular endosomal or lyso瑂omal vesicles membrane fusion by modify lipid components or fluidity.
• VP5 often catalyzes cell fusion, which facilitates the penetration of the endosomal membrane and consequently the release of outer capsid components.
• Upon ensuing " death domain " ( DD ) aggregation, the receptor complex is internalized via the cellular endosomal machinery.