fibrillarin造句

• Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
• Structural evidence supporting the idea that fibrillarin is the snoRNA methyltransferase has been reviewed.
• TBR17 was one of seventeen snoRNAs identified in " Trypanosoma brucei " by immunoprecipitation with anti-fibrillarin antibodies.
• TBR7 was one of seventeen snoRNAs identified in " Trypanosoma brucei " by immunoprecipitation with anti-fibrillarin antibodies.
• Fibrillarin is associated with U3, U8 and U13 small nuclear RNAs in mammals and is similar to the yeast NOP1 protein.
• The nucleolar staining pattern is associated with many antibodies including anti-Scl-70, anti-PM-Scl, anti-fibrillarin and anti-Th / To.
• Fibrillarin is a component of several ribonucleoproteins including a nucleolar small nuclear ribonucleoprotein ( SnRNP ) and one of the two classes of RNA splicing while snoRNPs function in ribosomal RNA processing.
• Fibrillarin has a well conserved sequence of around 320 amino acids, and contains 3 domains, an N-terminal Gly / Arg-rich region; a central domain resembling other RNA-binding proteins and containing an RNP-2-like consensus sequence; and a C-terminal alpha-helical domain.