gustducin造句

• Gustducin, a G protein second messenger, is activated . 3.
• An intriguing feature of gustducin is its similarity to transducin.
• Signal transduction of bitter stimuli is accomplished via the ?-subunit of gustducin.
• The taste receptor TAS1R3 and the taste G protein gustducin are two of the most common.
• This suggests that gustducin can interact with opsin and opsin-like G-coupled receptors.
• Gustducin is made of three subunits.
• Also, the terminal 38 amino acids of ?-gustducin and ?-transducin are identical.
• As with all TAS2R proteins, TAS2R38 utilizes the G-protein gustducin as its primary method of signal transduction.
• The ??-subunit of gustducin also mediates taste by activating IP 3 ( inositol triphosphate ) and DAG ( diglyceride ).
• When the ?-gustducin gene was re-inserted into the knock-out mice, the original taste ability returned.
• Sweetness is detected by a variety of G protein coupled receptors coupled to the G protein gustducin found on the taste buds.
• It was thought at the time that an alternative mechanism of bitter taste detection could be associated with the ?? subunit of gustducin.
• The ??-gustducin pathway continues with the activation of IP 3 receptors and the release of Ca 2 + followed by neurotransmitter release.
• The 1992 research also investigated the role of gustducin in bitter taste reception by using  knock-out mice lacking the gene for ?-gustducin.
• The 1992 research also investigated the role of gustducin in bitter taste reception by using  knock-out mice lacking the gene for ?-gustducin.
• The gustducin then activates the molecule adenylate cyclase, which catalyzes the production of the molecule cAMP, or adenosine 3', 5'- cyclic monophosphate.
• The structural similarities between gustducin and transducin are so great that comparison with transducin were used to propose a model of gustducin's role and functionality in taste transduction.
• The structural similarities between gustducin and transducin are so great that comparison with transducin were used to propose a model of gustducin's role and functionality in taste transduction.
• TAS1R1 and TAS1R2 receptors have been shown to bind to G proteins, most often the gustducin G? subunit, although a gustducin knock-out has shown small residual activity.
• TAS1R1 and TAS1R2 receptors have been shown to bind to G proteins, most often the gustducin G? subunit, although a gustducin knock-out has shown small residual activity.