isradipine造句

• Tagamet ( Cimetidine ) increased Isradipine mean peak plasma levels.
• The new study involved a calcium channel blocker known as isradipine, or DynaCirc.
• Some participants were treated with the drug isradipine, sold under the name DynaCirc.
• The company that markets isradipine, Sandoz Pharmaceuticals, insists the drug is safe.
• This will increase plasma levels of Isradipine and could cause an unintentional overdose of the medication.
• The study also found that isradipine offered no more benefit than the diuretic in slowing plaque buildup.
• The Food and Drug Administration has approved isradipine for the treatment of high blood pressure, or hypertension.
• The group taking isradipine suffered 25 such major vascular events, for an incidence of 5.65 percent.
• In a 1998 study, Johnson gave isradipine to volunteers an hour before they took a dose of cocaine.
• The study's researchers said that patients using isradipine to control high blood pressure should not stop taking it.
• And 11 isradipine patients suffered serious angina, chest pains associated with heart disease, compared to three diuretic patients.
• Isradipine interferes with dopamine release in these regions of the brain and causes blood vessels to relax, Johnson said.
• A small apparent increased risk of angina, heart attacks and strokes was found among those who took isradipine in the study.
• Addicts given cocaine were found to benefit from isradipine in specific areas of the brain that are rich in the brain chemical dopamine.
• Previous studies have linked deaths and heart attacks to some short-acting calcium channel blockers in the same sub-class as isradipine.
• Even though Isradipine, another Calcium Channel Blocker, has not been used in conjunction with Fentanyl anesthesia in any studies, caution is advised.
• Onmel / Sporanox ( Itraconazole ) exhibits a negative inotropic effect on the heart and thus could spur an additive effect when used concomitantly with Isradipine.
• Onmel / Sporanox also inhibits an important cytochrome liver enzyme ( CYP 450 3A4 ) which is needed to metabolize Isradipine and other Calcium Channel Blockers.
• Zanaflex ( Tizanidine ) demonstrates anti-hypertensive effects and should be avoided in patients taking Isradipine due to the possibility of synergism between both medications.
• Sandoz Pharmaceuticals Corp . of East Hanover, N . J ., makes isradipine, sells it as DynaCirc, and helped pay for the study.