lysosomotropic造句

• A significant part of the clinically approved drugs are lipophilic weak bases with lysosomotropic properties.
• The amount of accumulation of lysosomotropic compounds may be estimated using a cell-based mathematical model.
• Ambroxol is a lysosomotropic drug of clinical use to treat conditions of productive cough for its mucolytic action.
• Chloroquine is also a lysosomotropic agent, meaning it accumulates preferentially in the lysosomes of cells in the body.
• Its lysosomotropic properties further allow for its use for " in vitro " experiments pertaining to intracellular lipid related diseases, autophagy, and apoptosis.
• The lysosomotropic character of chloroquine is believed to account for much of its antimalarial activity; the drug concentrates in the acidic food vacuole of the parasite and interferes with essential processes.