machrs造句

• When a memorable event occurs, there is a massive release of acetylcholine that will attach to mAChRs.
• In the cat and rat, carbachol is well known for its ability to induce cholinergic receptors ( mAChRs ).
• Low doses of epibatidine will only affect the nAChRs, due to a higher affinity to nAChRs than to mAChRs.
• Higher doses, however, will cause epibatidine to bind to the mAChRs and result in paralytic effects in humans.
• The number of free and available muscarinic acetylcholine receptors ( mAChRs ) is highest when acetylcholine release is at the lowest levels.
• It competitively binds to the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists.
• Once too many are involved, the mAChRs will reduce or block further cholinergic input, which protects these cells and the networks from additional cholinergic input that could disrupt the signal.