mad2l2造句

• MAD2L1 is related to the MAD2L2 gene located on chromosome 1.
• MAD2L2 is a homolog of MAD2L1.
• MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate.
• The human orthologues of Mad2 ( MAD2L1 and MAD2L2 ) were first cloned in a search for human cDNAs that would rescue the microtubule poison-sensitivity of a yeast strain in which a kinetochore binding protein was missing.