myelinolysis造句

• A rapid rise in the sodium level may cause central pontine myelinolysis.
• The term " osmotic demyelination syndrome " is similar to " central pontine myelinolysis ", but also includes areas outside the pons.
• Hyponatremia should be corrected at a rate of no more than 8-12 mmol / L of sodium per day to prevent central pontine myelinolysis.
• This can cause a sudden and dramatic increase the serum sodium concentration and place the patient at risk for so-called " central pontine myelinolysis " ( CPM ).
• Central pontine myelinolysis was first described by Adams et al in 1958 as a clinicopathological entity . The original paper described four cases with fatal outcomes, and the findings on autopsy.
• Central pontine myelinolysis presents most commonly as a complication of treatment of patients with profound, life-threatening hyponatremia ( low sodium ), which may be the result of chronic or untreated polydipsia.
• Hyponatremia is corrected slowly, to lessen the risk of the development of central pontine myelinolysis ( CPM ), a severe neurological disease involving a breakdown of the myelin sheaths covering parts of nerve cells.
• The favourable factors contributing to the good outcome in a case of central pontine myelinolysis without hyponatremia were : concurrent treatment of all electrolyte disturbances, early Intensive Care Unit involvement at the advent of respiratory complications, early introduction of feeding including thiamine supplements with close monitoring of the electrolyte changes and input from the dietician