pemt造句
- The article about PEMT and this article are virtually the same topic.
- PEMT deficiency prevents artherosclerosis in mice fed high-fat, high-cholesterol diets.
- Another possibility is that lack of PEMT in adipose tissue may affect normal fat deposition.
- This is largely a result of lower levels of VLDL lipids in the PEMT-deficient mice.
- PEMT modulates levels of blood plasma homocysteine, which is either secreted or converted to methionine or cysteine.
- PEMT gene expression is regulated by transcription factors including promoter region may increase risk of hepatic steatosis from choline deficiency.
- PEMT deficiency in mice, genetically induced by PEMT gene knockout, produced minimal effect on PE and PC levels.
- PEMT deficiency in mice, genetically induced by PEMT gene knockout, produced minimal effect on PE and PC levels.
- The exact mechanism by which PEMT catalyzes the sequential methylation of PE by three molecules of SAM to form PC remains unknown.
- Purification of PEMT by Neale D . Ridgway and Dennis E . Vance in 1987 produced an 18.3 kDa protein.
- It's difficult to see pemt in a sentence. 用pemt造句挺难的
- PEMT-deficient mice fed high-fat diets have been shown to resist weight gain and be protected from insulin resistance.
- In humans it is encoded by the " PEMT " gene within the Smith-Magenis syndrome region on chromosome 17.
- Subsequent cloning, sequencing, and expression of PEMT cDNA resulted in a 22.3 kDa, 199-amino acid protein.
- The PEMT enzyme converts phosphatidylethanolamine ( PE ) to phosphatidylcholine ( PC ) via three sequential methylations by S-adenosyl methionine ( SAM ).
- A Val-to-Met substitution at residue 175, leading to reduced PEMT activity, has been linked to non-alcoholic fatty liver disease.
- Furthermore, the decreased lipid ( PC ) content in VLDLs causes changes in lipoprotein structure which allow them to be cleared more rapidly in the PEMT-deficient mice.
- It was concluded that insufficient choline resulted in the lack of weight gain, supported by the fact that PC produced via the PEMT pathway can be used to form choline.
- The human body can produce choline by methylation of phosphatidylethanolamine by N-methyltranferase ( PEMT ) to form phosphatidylcholine in the liver, or it may be consumed from the diet.
- This is exemplified by the observation that " Pemt-/-" mice ( mice lacking functional PEMT ) will abort at 9 10 days unless fed supplemental choline.
- This is exemplified by the observation that " Pemt-/-" mice ( mice lacking functional PEMT ) will abort at 9 10 days unless fed supplemental choline.